Advanced Microscopy Solutions for Cell Biology

NIS.ai

Discover the Power of Artificial Intelligence

Pre-Trained AI Modules:  Requires no user input or training.  Acquire crystal clear images with one click. 

  • Clarify.ai:  Recognizes and computationally removes out-of-focus fluorescence signal.  Apply to any widefield 2D or 3D data set, detector, or magnification.
  • Denoise.ai:  Removes shot noise for high-speed resonant scanned confocal images, in real-time.

User-Trainable AI Modules:  Train NIS-Elements to recognize features in un-labeled images and segment complex structures

  • Convert.ai:  Predicts staining patterns in un-labeled images.  Reconstruct a virtual DAPI channel from a non-fluorescent DIC image for cell segmentation.
  • Enhance.ai:  Restores details to low-signal images.  Acquire short-exposure images without compromising your ability to identify and segment objects.
  • Segment.ai:  Train NIS-Elements to automatically identify features that are previously only identifiable by painstaking manual tracing.

Easily Incorporate Into Your Imaging Pipeline

  • NIS.ai tools can be combined with all other features in NIS-Elements.
  • Utilize NIS.ai post-acquisition or as part of the acquisition workflow to develop data-driven imaging protocols.

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Advanced Confocal Imaging with A1R HD25

See the Bigger Picture

  • Market-leading 25mm field of view
  • Faster image stitching with fewer frames
  • Acquire ~2x the data in every frame for faster experiments and better statistics

High-Definition Images

  • The HD resonant scanner produces stunning images at incredible speeds.
  • Exclusive deconvolution algorithms for enhanced resolution

Powered by AI

  • Denoise.ai is pre-trained to recognize and remove shot noise from high-speed resonant-scanned images.  
  • No user-input required.  
  • Capture fast events without compromising image quality.
     

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A Full Range of Super-Resolution Solutions

Whether you are looking to apply super-resolution to live imaging, or understand macromolecular organization and protein interactions at the single molecule level, Nikon offers the widest range of super-resolution systems to choose from. 

  • N-SIM S:  High-speed, structured illumination-based system delivering 2x the resolution of traditional diffraction-limited microscopes (up to 115nm in XY).
  • N-STORM:  Single-molecule based system delivering 10x the resolution of standard light microscopes (up to 20nm in XY).
  • STEDYCON:  Stimulated Emission Depletion based system delivering over 6x higher resolution compared to conventional microscopes (~30-40nm resolution in XY).  Compact and alignment free, the STEDYCON scanner can be easily added to existing microscope systems. 
  • CSU-W1 SoRa:  Optical Pixel Reassignment based system providing 2x the resolution improvement (up to 120nm in XY).  Achieves enhanced resolution and confocal sectioning simultaneously. Ideal for high-speed, live-cell imaging.

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High-Content Imaging with BioPipeline Live

Flexible High-Content imaging platform with full environmental control for live samples.  

  • Customize:  Choose from a range of imaging modalities (e.g. widefield, point-scanning confocal, spinning-disk confocal, super-resolution), optics (e.g. automated water immersion) and detectors to meet your exact requirements.
  • Automated Plate Handling and Incubation:  Robotically transfers plates from a 44-plate capacity incubator to the microscope stage, all inside an incubated environmental enclosure. 
  • Scheduler:  Plate handling and imaging experiments are scheduled and executed by the NIS-Elements Scheduler.  Multiple users can easily schedule, execute and maintain their experiments with the Scheduler.
  • Dedicated Server: 10 GbE network connection for uninterrupted imaging and offline processing and analysis.
  • Powerful Analysis Toolbox:  Leverage AI-based tools to extract data from label-free images.  Integrate analysis into the acquisition pipeline for faster, data-driven HC experiments.

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FREE Nikon 2021 Small World Wall Calendar

The 2021 Nikon Small World wall calendar contains the winning images from Nikon’s 46th annual competition celebrating the beauty of photography through the microscope. The calendar is printed in full color on semi-gloss paper and spiral bound for mounting on the wall (size: 13"W x 10.5"H closed ; 13"W x 20"H opened).

If you’d like a free calendar, please fill out the form below and be sure to select ‘Nikon Small World Calendar’ and include your mailing address.

Offer good in the U.S. only and while supplies last.

Fill out the form below to request product information: